The Connecticut Department of Consumer Protection (DCP) is urging residents to store all medications safely and use them only as directed, with particular attention to over-the-counter products containing diphenhydramine, the active ingredient in Benadryl, amid concerns about misuse and accidental ingestion.

The advisory applies to a range of commonly available products including antihistamines, anti-diarrheals, cough syrups, and sleep aids such as Unisom and ZzzQuil. DCP has directed pharmacies across the state to share safe storage and proper dosage information with patients and to remain alert to unusual purchases of diphenhydramine, particularly by customers under age 18 or those buying large quantities. The department is also urging parents to speak directly with their children about the importance of following dosing instructions provided on medication packaging or by a medical professional.

"Diphenhydramine, most commonly associated with Benadryl, is an important over-the-counter medication that, when used properly, can help with allergic reactions and related symptoms," said DCP Commissioner Bryan T. Cafferelli. "But it is important to only use these and all over-the-counter medications according to package instructions and store them safely to prevent accidental ingestion and misuse, which can have serious health consequences."

DCP recommends that consumers keep medications in their original containers, store them out of sight and reach of children and pets, and use a locked cabinet, lockbox, or safe, particularly in households where someone has a substance use disorder or a history of self-harm. Residents are also advised to periodically review their medications and safely dispose of any that are unwanted or expired. Additional guidance on safe storage and disposal is available at the DCP’s website at https://portal.ct.gov/dcp/knowledge-base/articles/drug-control/patients/safe-storage-and-disposal.